| Synonyms |
* Oxibendazolum [INN-Latin],
* oxybendazole,
* (5-Propoxy-1H-benzimidazol-2-yl)carbamic acid methyl ester,
* N-(Propoxy-5, benzimidazolyl)-2, carbamate de methyle [French],
* 5-Propoxy-2-benzimidazolecarbamic acid methyl ester,
* AIDS-007902, * AIDS007902, * Anthelcide EQ,
* Carbamic acid, (5-propoxy-1H-benzimidazol-2-yl)-methyl ester,
* CHEMBANK758, * CHEMBANK907452,
* EINECS 243-877-7, * Filaribits Plus, * Loditac,
* Methyl 5-n-propoxy-2-benzimidazole carbamate,
* Methyl 5-propoxy-2-benzimidazolecarbamate, * MLS000069646,
* N-(2-(5-Propoxybenzimidazolyl)) methyl carbamate,
* Oxibendazole, * Oxibendazole [USAN:BAN:INN], *Oxibendazolo [INN-Spanish], * SK&F 30310, * SKF 30310, * SMR000058208, |
Pharmacodynamic
Properties |
Oxibendazole acts by disrupting the generation of ATP and irreversibly inhibiting glucose uptake in the gastro-intestinal worms resulting in a depletion of the worm’s energy sources and their slow death.
Oxibendazole is a benzimidazole anthelmintic used in the treatment of roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and other ruminants. The drug was highly effective against adult large strongylids (Strongylus vulgaris, S edentatus, S equins), adult small strongylids (especially species of the genera Cylicostephanus, Cylicocyclus, Cyaathostomum, and Triodontophorus), and adult and larval stages of the large pinworm, Oxyuris equi. |