Jiangsu Quality Horizons Pharmtech Co., Ltd.--Febantel

Jiangsu Quality Horizons

Our Spirit: Responsibility, Efficiency, Team work, Creativity;
Our Mission: Devoted to the manufacturing of anthelmintics and to be the industrial leader;
Our Vision: To be a guardian of health;
Our Value: Responsible for the customer, Responsible for the staff,Responsible for the society, Responsible for the shareholders.

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Febantel

Synonyms	* ((2-((Methoxyacetyl)amino)-4-(phenylthio)phenyl)carbonimidoyl)bis(carbamic acid), dimethyl ester, * CARBAMIC ACID, ((2-((METHOXYACETYL)AMINO)-4-(PHENYLTHIO)PHENYL)CARBONIMIDOYL)BIS, * Carbamic acid, ((2-((methoxyacetyl)amino)-4-(phenylthio)phenyl)carbonimidoyl)bis-, dimethyl ester, * Dimethyl ((2-(2-methoxyacetamido)-4-(phenylthio)phenyl)imidocarbonyl)dicarbamate, * EINECS 261-205-0, * Febantel [USAN:BAN:INN], * Febantelum [INN-Latin], * N-(2-(2,3-Bis-(methoxycarbonyl)-guanidino)-5-(phenylthio)-phenyl)-2-methoxyacetamide, * Negabot Plus Paste, * Oratel, * Rintal, * DrontalPlus
Chemical Name	Dimethyl [[2-[(methoxyacetyl)amino]-4-(phenylthio)phenyl]carbonimidoyl] biscarbamate
Molecular formula	C₂₀H₂₂N₄O₆S
Molecular weight	446.48
CAS No.	58306-30-2
Structural formula
Specification	EP
Pharmacodynamic Properties	The mechanism of Febantel action is primarily based on interference with the carbohydrate metabolism of the worm. The suppression of mitochondrial reactions (inhibition of fumarate reductase) and interferencewith glucose transport act not only on all developmental stages of the helminths but also on the eggs containing the larvae. Benzimidazoles bind to the structural protein tubulin, thereby preventing its polymerization to microtubules which provide the transport system for the absorbing cells. The consequence of blocking this transport activity is incomplete absorption and digestion of nutrient particles and cellular autolysis through activation of lysosomal enzymes. Febantel is a broad-spectrum anthelmintic, it is active against nematode parasites including whipworms.
Storage	Keep container tightly closed in a cool, well-ventilated area
MSDS	Provide as per request after the order or contract is signed.

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