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Oxyclozanide

Synonyms * Oxyclozanid, * Oxiclozanida [INN-Spanish], * Oxiclozanidum,
* Oxyclozanidum [INN-Latin], * Oxyclozanide [BAN:INN],
* 2,2'-Dihydroxy-3,3',5,5',6-pentachlorobenzanilide,
* 3,3',5,5',6-Pentachloro-2'-hydroxysalicylanilide,
* 3,3',5,5',6-Pentachloro-2,2'-dihydroxybenzanilide,
* 3,5,6,3',5'-Pentachloro-2,2'-dihydroxybenzanilide,
* Benzamide, 2,3,5-trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxy-(9CI),
* Benzanilide, 2,2'-dihydroxy-3,3',5,5',6-pentachloro-,
* BRN 2014120, * CCRIS 5744, * Diplin,
* EINECS 218-904-0, * ICI 46638,
* Salicylanilide, 3,3',5,5',6-pentachloro-2'-hydroxy-,
* Zanil, * Zanilox,
Chemical Name 2,3,5-trichloro-N-(3,5-dichloro-2-hydroxy-phenyl)-6-hydroxy-benzamide
Molecular formula C13H6Cl5NO3
Molecular weight 401.455
CAS No. 2277-92-1
Structural formula
Specification BPV
Pharmacodynamic Properties Oxyclozanide is an anthelmintic of the salicylanilide group. It is effective against Fasciola, tapeworm and cestode infestations, acting as an uncoupler of oxidative phosphorylation. It may act at more than one site to decrease levels of ATP leading to metabolic malfunction and death of the parasite.
Oxyclozanide is slowly absorbed after oral administration with peak plasma levels 24 hours after dosing. Excretion is predominantly faecal.
Storage Keep container tightly closed in a cool, well-ventilated area.
MSDS Provide as per request after the order or contract is signed.

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